Substrate binding modulates the conformational kinetics of the secondary multidrug transporter LmrP
A. Roth, C. Martens, T. van Oene, A. Barth, S. Wanninger, D. C. Lamb, J. Hendrix, C. Govaerts
This study uses smFRET to show substrate binding modulates conformational kinetics of LmrP, revealing substrate-dependent structural changes in MFS transporters.
bioRxiv · Apr 9, 2020 · PreprintBiophysics