Replication fork collapse at a protein-DNA roadblock leads to fork reversal, promoted by the RecQ helicase
G. Weaver, K. Mettrick, T.-A. Corocher, A. Graham, I. Grainge, No
This study shows that replication fork reversal (RFR) is the preferred pathway for dealing with a collapsed replication fork in Escherichia coli, with RecQ helicase playing the main role in processing the resulting Holliday junction.
bioRxiv · May 14, 2018Microbiology