Discovery of a pentose as a cytosine nucleobase modification in Shewanella phage Thanatos-1 genomic DNA mediating enhanced resistance towards host restriction systems
David Brandt, Anja K. Dörrich, Marcus Persicke, Tabea Leonhard, Markus Haak, Sophia Nölting, Matthias Ruwe, Nicole Schmid, Kai M. Thormann, Jörn Kalinowski
The paper identifies a novel pentose modification on cytosine in phage DNA that enhances resistance to host restriction systems.
bioRxiv · Feb 27, 2024 · PreprintMolecular Biology