Phenome-Wide Association of APOE Alleles in the All of Us Research Program
Ehsan Khajouei, Valentina Ghisays, Ignazio Stefano Piras, Kiana L. Martinez, Anthony T. Vicenti, Marcus Naymik, Preston Ngo, Tam C. Tran, Joshua C. Denny, Travis J. Wheeler, Matthew J. Huentelman, Eric M. Reiman, Jason H. Karnes
This study performs a phenome-wide association analysis of APOE alleles in the All of Us Research Program, identifying significant associations with various health outcomes and highlighting sex and ancestry differences.
EBioMedicine · May 30, 2025Peer-reviewedGenetic & Genomic Medicine