Author

Tatsuya Corlett

Earth-Life Science Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:mechanistic / dynamical model· 1 Assay:metabolomics· 1 Assay:protein structure· 1

Frequent Co-Authors

Liam M. LongoiD· 2 shared Andre Lecona ButtelliiD· 1 shared Claudèle Lemay-St-DenisiD· 1 shared Eric A. SmithiD· 1 shared Eric SmithiD· 1 shared Hamza Giaffar· 1 shared Harrison B. SmithiD· 1 shared Joshua E. GoldfordiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Liam M. LongoORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Nucleotide-binding motifs nucleated folding of the first enzymes

Koh Seya, Tatsuya Corlett, Hamza Giaffar, Andre Lecona Buttelli, Claudèle Lemay-St-Denis, Kosuke Fujishima, Shina Caroline Lynn Kamerlin, Rachel Kolodny, Eric Smith, Liam M. Longo

This study investigates the emergence of two key cofactor-binding protein folds by analyzing their metabolic roles, structural organization, and folding mechanisms.

bioRxiv · Aug 11, 2026 · PreprintBiochemistry

The History of Enzyme Evolution Embedded in Metabolism

Tatsuya Corlett, Harrison B. Smith, Eric A. Smith, Joshua E. Goldford, Liam M. Longo

This paper reconstructs the historical emergence of enzymatic folds using metabolic reaction networks, finding that enzyme evolution is embedded in metabolic interdependencies and that β-proteins dominated early metabolism.

Proceedings of the National Academy of Sciences · Aug 11, 2026Peer-reviewedBioinformatics