Inhibition of the phosphoinositide 3-kinase-AKT-cyclic GMP-c-Jun N-terminal kinase signaling pathway attenuates the development of morphine tolerance in a mouse model of neuropathic pain
Travis Okerman, Taylor Jurgenson, Madelyn N. Moore, Amanda H. Klein
This study shows that inhibiting the PI3K-AKT-cGMP-JNK pathway reduces morphine tolerance in a mouse model of neuropathic pain.
Molecular Pain · Jan 1, 2021Peer-reviewedNeuroscience