Multi-objective domain adaptation for pan-cancer transfer of pharmacogenomic drug response to patient tumours
Vittorio Fortino, Teemu Joel Rintala
This paper introduces MODAE+, a multi-objective domain adaptation framework that improves drug response prediction across cancer cell lines and patient tumours by preserving biological structure and heterogeneity.
bioRxiv · Nov 5, 2026 · PreprintBioinformatics