Effect of ancestry and shared genetic architecture of serious mental illness on symptoms and cognition in an admixed Latin American population
Nelson B. Freimer, Esteban A. Lopera-Maya, Susan Service, Ana Diaz-Zuluaga, Mauricio Castano Ramirez, Juan Mejia, Johanna Valencia Echeverry, Terri Teshiba, Ana Ramírez, Juan De La Hoz, Jonathan Valdez, Marfred Munoz Umanes, Tyler M. Moore, Sinéad B. Chapman, Benjamin M. Neale, , Carlos López-Jaramillo
The paper shows that European GWAS findings for serious mental illness and cognition are portable to an admixed Latin American population, associating genetic risk scores with multiple symptoms and cognitive traits.
medRxiv · May 7, 2026 · PreprintGenetic & Genomic Medicine