Author

Thanh V. T. Tran

FPT University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

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Research Focus:protein design· 1 Assay:protein sequence· 1 Approach:variational autoencoder· 1

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Nhat Khang NgoiD· 1 shared Truong Son HyiD· 1 shared Viet Thanh Duy NguyeniD· 1 shared

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2024-2024 · peak 1/yr

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Nhat Khang NgoORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintApr 13, 2024

Latent-based Directed Evolution accelerated by Gradient Ascent for Protein Sequence Design

Nhat Khang Ngo, Thanh V. T. Tran, Viet Thanh Duy Nguyen, Truong Son Hy

This paper introduces LDE, a variational autoencoder-based method for protein sequence design that improves efficiency by prioritizing high-fitness mutants in latent space, outperforming baselines on eight tasks.

DOI 10.1101/2024.04.13.589381

protein sequencevariational autoencoder

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