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Genomics· 1

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Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

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Chenghang ZongiD· 1 shared Christopher M GrochowskiiD· 1 shared Eric VenneriD· 1 shared Fritz J. SedlazeckiD· 1 shared Harsha DoddapaneniiD· 1 shared Jesse FarekiD· 1 shared Luis F. PauliniD· 1 shared Marie-Claude GingrasiD· 1 shared

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1 shared paperGenomics

Chenghang ZongORCID

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1 paper

Recent·Most cited

GenomicsbioRxivPreprintNov 13, 2026

An oxidative mutational signature in normal tissues of a monoallelic MUTYH carrier

Christopher M Grochowski, Yang Zhang, Eric Venner…·Richard A. Gibbs

The paper identifies an oxidative mutational signature in normal tissues of individuals carrying a single pathogenic MUTYH allele, suggesting a measurable mutational risk in healthy tissues.

DOI 10.64898/2026.11.12.766009

humanwhole-genome sequencing

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