Germline De Novo Mutation Clusters Arise During Oocyte Aging In Genomic Regions With Increased Double-Strand Break Incidence
Jakob M. Goldmann, Vladimir B. Seplyarskiy, Wendy S.W. Wong, Thierry Vilboux, Pieter B. T. Neerincx, Dale L. Bodian, Benjamin D. Solomon, Joris Andre Veltman, John F. Deeken, Christian Gilissen, John E. Niederhuber
The paper identifies maternal age-related mutation clusters in germline de novo mutations linked to double-strand break processes.
Nature Genetics · Mar 1, 2018Peer-reviewedGenomics