X-chromosome methylation patterns in females with multiple sclerosis
Thomas Calnin, Vicki E. Maltby, Sean M. Burnard, Alexandre Xavier, Steve Simpson, Ingrid A.F. van der Mei, Simon Broadley, Bruce V. Taylor, Helmut Butzkueven, Anne-Louise Ponsonby, Rodney John Scott, Maja Jagodic, Vilija Jokubaitis, Jeannette Lechner‐Scott, Rodney A. Lea
This study identifies X-chromosome hypomethylation in female MS patients and links it to XCI escape genes and immune processes.
medRxiv · Oct 14, 2026 · PreprintGenetic & Genomic Medicine