Medial prefrontal cortical NMDA receptors regulate depression-like behavior and dictate limbic thalamus innervation
Oliver H Miller, Andreas Bruns, Imen Ben Ammar, Thomas Mueggler, Benjamin J. Hall
This study shows that deleting GluN2B from medial prefrontal cortex pyramidal neurons enhances synaptic activity and promotes antidepressant-like behavior in mice.
Cell Reports · Aug 1, 2017Peer-reviewedNeuroscience