Summary-data-based mendelian randomisation reveals druggable targets for multiple sclerosis
Benjamin M. Jacobs, Thomas Taylor, Amine Mohamed Marc Awad, David Baker, Gavin Giovanonni, Alastair John Noyce, Ruth Dobson
This paper uses summary-data-based Mendelian randomisation to identify druggable genetic targets for multiple sclerosis, finding 15 genes with causal links between methylation, expression, and disease susceptibility.
bioRxiv · Jan 20, 2020 · PreprintGenetics