Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model
Hanzhi Yu, Guorong Zhang, Yunxi Ma, Tianrui Ma, Shanshan Wang, Jiayu Ding, Jingjing Liu, Zilong Zhao, Zhiliang Zhou, Shaozhuo Jiao, Ge Dong, Zhigang Cai
This study uses single-cell and spatial transcriptomics to analyze granuloma formation in a natural CGD mouse model and identifies therapeutic targets.
Cell Reports · Apr 22, 2025Peer-reviewedImmunology