Author

Yunxi Ma

State Key Laboratory of Experimental Hematology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Zhigang CaiiD· 3 shared Huaquan WangiD· 2 shared Lorie Chen Cai· 2 shared Yuchen Wen· 2 shared Baobing ZhaoiD· 1 shared Dengyi Bao· 1 shared Ge DongiD· 1 shared Ge Dong· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersImmunology

Zhigang CaiORCID

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3 papers

Recent·Most cited

Disturbing immune homeostasis by neutrophil loss of Uba1 induces VEXAS-like autoinflammatory disease in mice

Ge Dong, Jingjing Liu, Hongxi Zhou, Wenyan Jin, Yuchen Wen, Zhiqin Wang, Keyao Xia, Jianlin Zhang, Li Ma, Yunxi Ma, Lorie Chen Cai, Qiufan Zhou, Huaquan Wang, Wei Wei, Ying Fu, Zhigang Cai

This study shows that neutrophil loss of Uba1 in mice causes VEXAS-like autoinflammatory disease, with symptoms including increased neutrophils, cytokines, and vacuoles.

Journal of Clinical Investigation · Sep 4, 2025Peer-reviewedImmunology

Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model

Hanzhi Yu, Guorong Zhang, Yunxi Ma, Tianrui Ma, Shanshan Wang, Jiayu Ding, Jingjing Liu, Zilong Zhao, Zhiliang Zhou, Shaozhuo Jiao, Ge Dong, Zhigang Cai

This study uses single-cell and spatial transcriptomics to analyze granuloma formation in a natural CGD mouse model and identifies therapeutic targets.

Cell Reports · Apr 22, 2025Peer-reviewedImmunology

Computing hematopoiesis plasticity in response to genetic mutations and environmental stimulations

Yuchen Wen, Hang He, Yunxi Ma, Dengyi Bao, Lorie Chen Cai, Huaquan Wang, Yanmei Li, Baobing Zhao, Zhigang Cai

This study introduces a computational pipeline to quantify hematopoietic cell plasticity using single-cell RNA-seq data and identifies factors influencing plasticity under genetic and environmental stress.

Life Science Alliance · Nov 13, 2024Peer-reviewedDevelopmental Biology