Pharmacology & ToxicologyInternational Journal of Biological MacromoleculesPeer-reviewed
Discovery of a Novel Chemotype as DYRK1A Inhibitors against Alzheimer's disease: Computational Modeling and Biological Evaluation
Nianzhuang Qiu, Chenliang Qian, Tingting Guo…·Jie Xia
This paper identifies a novel DYRK1A inhibitor, compound Q17, through computational screening and validates its efficacy in reducing AD-related pathology in vitro and in vivo.
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