Multimodal 3D imaging reveals a central role for lysosomes indissolution of cholesterol crystals by macrophages
Vibeke Akkerman, Alice Dupont Juhl, Jacob Marcus Egebjerg, Christoph Pratsch, Stephan Werner, Gerd Schneider, Tido Willms, Peter (1791 - 1877) Müller, Sergey Kapishnikov, Daniel Wüstner
This study uses multimodal 3D imaging to show that lysosomes dissolve cholesterol crystals in macrophages, with cyclodextrin enhancing this process.
bioRxiv · Sep 23, 2026 · PreprintBiochemistry