Characterization of the Mitomycin C Resistance Protein McrA
Gwen Tjallinks, Tomás Dunleavy, Tim Jonker, Nicolò Angeleri, Andrea Mattevi, Marco W. Fraaije
This study characterizes McrA, a flavin-dependent enzyme from Streptomyces lavendulae, showing it oxidizes mitomycin C to prevent its toxic effects.
bioRxiv · Nov 28, 2025 · PreprintBiochemistry