Mutation detection in thousands of acute myeloid leukemia cells using single cell RNA-sequencing
Allegra A. Petti, Stephen R. Williams, Christopher A. Miller, Ian T. Fiddes, Sridhar N. Srivatsan, David Y. Chen, Catrina C. Fronick, Robert S. Fulton, Deanna M. Church, Timothy J. Ley
This paper links subclonal mutations to transcriptional profiles in AML using integrated single-cell RNA-sequencing and whole genome sequencing.
bioRxiv · Oct 17, 2018 · PreprintCancer Biology