Christopher A. Miller

This paper uses long-read cDNA sequencing to identify novel transcripts and spliceosome-mutant-enriched isoforms in AML and MDS, providing a resource for improving short-read RNA-seq analyses.

This study uses ultra-deep exome sequencing to identify recurrent mutations in classical Hodgkin lymphoma HRS cells, demonstrating its utility for analyzing genomic variants in large patient cohorts.

The paper predicts MHC anchor positions for 328 HLA alleles and shows that incorporating these improves neoantigen identification by correcting misclassified candidates in tumor samples.

The paper identifies a GRCh38 reference sequence change that prevents detection of U2AF1 mutations and provides a modified reference to address this issue.

This study shows that Kdm6a deficiency in mouse hematopoietic cells leads to age- and sex-dependent myelodysplastic syndrome-like features without overt leukemia.

pVACtools provides a suite of tools for neoantigen prediction, prioritization, and vaccine design in cancer immunotherapy.

This paper links subclonal mutations to transcriptional profiles in AML using integrated single-cell RNA-sequencing and whole genome sequencing.

The paper identifies somatic mutations with prognostic effects in ER+ breast cancer using genomic data from multiple cohorts.