Decoupling the impact of microRNAs on translational repression versus RNA degradation in embryonic stem cells
Jacob W. Freimer, TJ Hu, Robert H. Blelloch
The paper investigates the role of DDX6 in linking microRNA functions to mRNA stability and translation in ESCs, finding that DDX6 loss separates microRNA's translational repression from transcript destabilization.
eLife · Jul 25, 2018Peer-reviewedGenetics