Medial prefrontal cortex Notch1 signalling mediates methamphetamine-induced psychosis via Hes1-dependent suppression of GABAB1 receptor expression.
Tong Ni, Li Zhu, Shuai Wang, Weili Zhu, Yan-Xue Xue, Yingjie Zhu, Dongliang Ma, Hongyan Wang, Fanglin Guan, Teng Chen
This study identifies a Notch1-Hes1-GABAB1 receptor pathway in the medial prefrontal cortex that mediates methamphetamine-induced psychosis by suppressing GABAB1 expression.
Molecular Psychiatry · Jun 22, 2022Peer-reviewedMolecular Biology