Lysine-R2HGylation identified as a post-translational modification in R2HG-elevated cancers
Qian Zhao, Peiwu Huang, Changhao Yuan, Peng Xia, Qiang‐Shuai Gu, Tonghua Yang, Xiang Li, Ruijun Tian, Dan Yang
The paper identifies lysine-R2HGylation as a new post-translational modification driven by R2HG in cancers, showing its impact on GSTP1 activity and monocyte differentiation.
bioRxiv · Oct 3, 2025 · PreprintMolecular Biology