Brain aerobic glycolysis and resilience in Alzheimer disease
Manu S. Goyal, Tyler Blazey, Nicholas V. Metcalf, Mark P. McAvoy, Jeremy F. Strain, Maryam Rahmani, Tony J. Durbin, Chengjie Xiong, Tammie L.S. Benzinger, John C. Morris, Marcus E. Raichle, Andrei G. Vlassenko
This study finds that preserved aerobic glycolysis in the brain is linked to resilience against Alzheimer's disease pathology, while white matter hyperintensity burden is associated with reduced youthful AG patterns.
Proceedings of the National Academy of Sciences · Feb 6, 2023Peer-reviewedNeuroscience