The Endothelin Receptor Antagonist Macitentan Ameliorates Endothelin-Mediated Vasoconstriction and Promotes Neuroprotection of Retinal Ganglion Cells in Rats
Dorota L. Stankowska, Wei Zhang, Shaoqing He, Vignesh R. Krishnamoorthy, Payton E. Harris, Trent Hall, Renuka M. Chaphalkar, Bindu Kodati, Sai H. Chavala, Raghu R. Krishnamoorthy
This study shows that macitentan reduces ET-1-induced vasoconstriction and protects retinal ganglion cells in rats.
bioRxiv · Oct 27, 2020 · PreprintNeuroscience