A Real Time Quaking Induced Conversion (RT-QuIC) Assay for Detection of Misfolded Insulin Protein
Jessica M Alderiso, Rafael Hernandez LaTorre, Trisha M. Cox, Matthew G Digiovanni, Keileigh Fulbright, Brenda Canine
The paper develops an RT-QuIC assay to detect misfolded insulin and applies it to study insulin aggregation in a mouse model of metabolic disease.
bioRxiv · Apr 11, 2026 · PreprintMolecular Biology