Author

Tsutomo Kume

Northwestern University

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Biology Disciplines

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Developmental Biology· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Asra Almubarak· 1 shared Devi Priyanka MaripuriiD· 1 shared Fred B. BerryiD· 1 shared Nikola SrniciD· 1 shared Rotem Lavy· 1 shared Yawen Hu· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperDevelopmental Biology

Asra Almubarak

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1 paper

Recent·Most cited

Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification.

Asra Almubarak, Rotem Lavy, Nikola Srnic, Yawen Hu, Devi Priyanka Maripuri, Tsutomo Kume, Fred B. Berry

This study shows that Foxc1 and Foxc2 are essential for chondrocyte differentiation and endochondral ossification, with their loss causing skeletal dysplasia and disrupted growth plate organization.

Journal of Biological Chemistry · Jul 28, 2021Peer-reviewedDevelopmental Biology