Molecular BiologyNature CommunicationsPeer-reviewed
KLF4 Recruits SWI/SNF to Increase Chromatin Accessibility and Reprogram the Endothelial Enhancer Landscape under Laminar Shear Stress
Jan-Renier A. J. Moonen, James Chappell, Minyi Shi…·Marlene Rabinovitch
The paper shows how KLF4 interacts with SWI/SNF to increase chromatin accessibility at enhancers under laminar shear stress, promoting endothelial homeostasis and suppressing inflammation.