New-to-nature PHA synthase design using deep learning
Tuula Tenkanen, A. Ylinen, Paula Jouhten, Merja E. Penttilä, Sandra Castillo
This study uses a conditional variational autoencoder to design new-to-nature PHA synthases, which are validated for activity in yeast and show potential for expanding PHA material properties.
PLoS Computational Biology · Mar 19, 2026Peer-reviewedBioengineering