Author

Merja E. Penttilä

VTT Technical Research Centre of FinlandORCID 0000-0002-6929-1032Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:metabolomics· 1 Research Focus:protein design· 1

Frequent Co-Authors

Paula JouhteniD· 2 shared A. YlineniD· 1 shared Juho RousuiD· 1 shared Markus B. LinderiD· 1 shared Maryam SabzevariiD· 1 shared Pezhman MohammadiiD· 1 shared Sándor SzedmákiD· 1 shared Sandra CastilloiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBioengineering

Paula JouhtenORCID

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3 papers

Recent·Most cited

New-to-nature PHA synthase design using deep learning

Tuula Tenkanen, A. Ylinen, Paula Jouhten, Merja E. Penttilä, Sandra Castillo

This study uses a conditional variational autoencoder to design new-to-nature PHA synthases, which are validated for activity in yeast and show potential for expanding PHA material properties.

PLoS Computational Biology · Mar 19, 2026Peer-reviewedBioengineering

Strain design optimization using reinforcement learning

Maryam Sabzevari, Sándor Szedmák, Merja E. Penttilä, Paula Jouhten, Juho Rousu

This paper uses multi-agent reinforcement learning to optimize microbial strain production, showing improved convergence and stability in synthetic biology applications.

PLoS Computational Biology · Jun 3, 2022Peer-reviewedBioinformatics

Analysis of Finnish blue mussel (Mytilus edulis L.) shell: Biomineral ultrastructure, organic-rich interfacial matrix and mechanical behavior

Pezhman Mohammadi, Wolfgang Wagermaier, Merja E. Penttilä, Markus B. Linder

This study characterizes the ultrastructure, organic matrix, and mechanical properties of the shell of the Finnish blue mussel, revealing structural gradients and unique biomineralization features.

bioRxiv · Aug 12, 2019 · PreprintDevelopmental Biology