Functional diversity of PFKFB3 splice variants in glioblastomas
U. Heydasch, R. Kessler, J.-P. Warnke, K. Eschrich, N. Scholz, M. Bigl
This study investigates the functional roles of PFKFB3 splice variants in glioblastomas, finding variant-specific effects on cell viability and proliferation, with PFKFB3-4 promoting and PFKFB3-5 inhibiting tumor growth.
bioRxiv · Oct 9, 2020 · PreprintCancer Biology