BiophysicsbioRxiv
Water-mediated interactions enable smooth substrate transport in a bacterial efflux pump
A. V. Vargiu, V. K. Ramaswamy, I. Malvacio…·P. Ruggerone
The paper investigates the role of water-mediated interactions in the substrate transport mechanism of the bacterial efflux pump AcrB, revealing how structured waters facilitate substrate diffusion.
DOI 10.1016/j.bbagen.2018.01.010