Strength of purifying selection on the amino-acid sequence is associated with the amount of non-additive variance in gene expression.
Margarita Takou, Daniel J. Balick, Kim A. Steige, Josselin Clo, Hannes Dittberner, Ulrike Goebel, Holger Schielzeth, Juliette de Meaux
The study finds that genes with higher non-additive variance in expression show stronger purifying selection and lower synonymous variation in Arabidopsis lyrata.
bioRxiv · Feb 11, 2022 · PreprintEvolutionary Biology