The unique tropism of Mycobacterium leprae to the nasal epithelial cells can be explained by the mammalian cell entry protein 1A
V. B. FADLITHA, F. YAMAMOTO, I. IDRIS, H. DAHLAN, N. SATO, V. B. AFTITAH, A. FEBRIYANDA, T. Fujimura, H. TAKIMOTO
This study identifies the InvX region of M.leprae's mce1A protein as critical for epithelial cell entry, distinct from the InvIII region in M.tuberculosis.
bioRxiv · Jul 20, 2018Microbiology