Conformational entropy of intrinsically disordered proteins bars intruders from biomolecular condensates
V. Grigorev, N. S. Wingreen, Y. Zhang
The paper shows that intrinsically disordered regions (IDRs) in biomolecular condensates exclude intruders via conformational entropy, with exclusion efficiency increasing with IDR concentration and intruder size.
bioRxiv · Mar 3, 2023 · PreprintBiophysics