Accurate Microbiome Sequencing with Synthetic Long Read Sequencing
N. Chung, M. W. Van Goethem, M. A. Preston, F. Lhota, L. Cerna, F. Garcia-Pichel, V. M. C. Fernandes, A. Giraldo-Silva, H. S. Kim, E. Hurowitz, M. Balamotis, I. Wu, T. Ben Yehezkel
This paper evaluates a synthetic long-read sequencing approach for accurate 16S rRNA gene sequencing, showing improved phylogenetic resolution and accuracy over short-read methods.
bioRxiv · Oct 2, 2020 · PreprintMicrobiology