H. S. Kim

Biocomposite Thermoplastic Polyurethanes Containing Evolved Bacterial Spores as Living Fillers to Facilitate Polymer Disintegration

This paper develops biocomposite thermoplastic polyurethanes containing heat-tolerant bacterial spores that enable polymer disintegration and retain programmed functions.

Altered CD8+ T cell associated aging gene signature in the peripheral blood of patients with Alzheimer's disease.

The paper examines gene expression in CD8+ T cells from Alzheimer's patients and finds altered levels of age-associated genes linked to cognitive decline.

Two Interaction Surfaces between XPA and RPA Organize the Preincision Complex in Nucleotide Excision Repair

The paper investigates two interaction surfaces between XPA and RPA in the preincision complex of nucleotide excision repair, showing their distinct roles in complex assembly and NER activity.

Emergence of glycogen synthase kinase-3 interaction domain enhances phosphorylation of SARS-CoV-2 nucleocapsid protein

This study identifies a GSK-3 interacting domain in SARS-CoV-2 N protein that enhances its phosphorylation, with mutations in variants like Delta and Omicron increasing N abundance and phosphorylation.

Comparison of Plaque Size, Thermal Stability, and Replication Rate among SARS-CoV-2 Variants of Concern

This study compares plaque size, thermal stability, and replication rates of four SARS-CoV-2 variants of concern and finds differences in these characteristics among them.

In vitro validation of neoantigen prediction algorithm for developing personalized cancer vaccine therapy

The paper validates a neoantigen prediction algorithm, Neopepsee, by testing its immunogenicity using ELISpot assays on patient-derived samples and compares it to pVACseq.

BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking CLU+ CAF expression with HSF1 signaling

This study shows BRCA mutations in pancreatic cancer alter CAF subtypes, specifically increasing CLU+ CAFs, and links this to HSF1 signaling.

Comparison of everting sutures and the lateral tarsal strip with or without everting sutures for involutional lower eyelid entropion: A meta-analysis

This study compares the recurrence rates of involutional lower eyelid entropion correction using everting sutures alone versus lateral tarsal strips with or without everting sutures, finding the latter significantly reduces recurrence.

Accurate Microbiome Sequencing with Synthetic Long Read Sequencing

This paper evaluates a synthetic long-read sequencing approach for accurate 16S rRNA gene sequencing, showing improved phylogenetic resolution and accuracy over short-read methods.

KMT2D Links TGF-β Signalling to Non-Canonical Activin Pathway and Regulates Pancreatic Cancer Cell Plasticity

This study identifies KMT2D as a tumor suppressor in pancreatic cancer, linking TGF-β signaling to the non-canonical activin A pathway through miR-147b and showing its role in cancer cell plasticity and metastasis.

The Glycolytic Protein Phosphofructokinase Dynamically Relocalizes into Subcellular Compartments with Liquid-like Properties in vivo

This study shows that PFK-1.1 dynamically forms liquid-like condensates in neurons under energy stress, revealing a new mechanism for subcellular organization.

Impact of Direct Acting Antivirals on Survival in Patients with Chronic Hepatitis C and Hepatocellular Carcinoma

This study shows that direct-acting antivirals (DAAs) and achieving SVR12 improve survival in HCV-positive patients with hepatocellular carcinoma.

METABOLIC DIVERSITY IN HUMAN NON-SMALL CELL LUNG CANCER CELLS

The paper quantifies metabolic features in NSCLC cell lines to explore associations between metabolism and other cell-autonomous processes.

Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer

This study identifies endocytosis-related gene polymorphisms in breast cancer and suggests alpha-cyclodextrin as a potential treatment to inhibit metastasis and exosome packaging.

Oncogenic role of sFRP2 in P53-mutant osteosarcoma development via autocrine and paracrine mechanism

This study identifies sFRP2 as an oncogenic driver in P53-mutant osteosarcoma through autocrine and paracrine mechanisms, showing its role in promoting tumor growth and poor survival.