SERS uncovers the link between conformation of cytochrome c heme and mitochondrial membrane potential
N. A. Brazhe, E. I. Nikelshparg, A. A. Baizhumanov, V. G. Grivennikova, A. A. Semenova, S. M. Novikov, V. S. Volkov, A. V. Arsenin, D. I. Yakubovsky, A. B. Evlyukhin, Z. V. Bochkova, E. A. Goodilin, G. V. Maksimov, O. Sosnovtseva, A. B. Rubin
This paper develops a SERS-based sensor to detect conformational changes in cytochrome c heme and links these changes to mitochondrial membrane potential and ETC activity.
bioRxiv · Jan 3, 2021Biophysics