Revealing Chloroquine's Antimalarial Mechanism: The Suppression of Nucleation Events during Heme to Hemozoin Transformation
R. Singh, R. Singh, V. Srihari, R. D. Makde
This study shows chloroquine delays hemozoin production by perturbing nucleation events rather than inhibiting crystal growth or substrate availability.
bioRxiv · Jun 15, 2023 · PreprintBiochemistry