Author

V. Tragni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:protein structure· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. De Grassi· 2 shared C. L. Pierri· 2 shared A. Onofrio· 1 shared F. Busto· 1 shared F. Preziusi· 1 shared I. Mercurio· 1 shared L. Laera· 1 shared M. Volpicella· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 26 mutual co-author links

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2 shared papersBiochemistry

A. De Grassi

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2 papers

Recent·Most cited

A modular molecular framework for quickly estimating the binding affinity of the spike protein of SARS-CoV-2 variants for ACE2, in presence of mutations at the spike receptor binding domain.

V. Tragni, F. Preziusi, L. Laera, A. Onofrio, S. Todisco, M. Volpicella, A. De Grassi, C. L. Pierri

The paper presents a computational pipeline to estimate binding affinities of SARS-CoV-2 spike protein variants for ACE2, identifying potential new host factors involved in viral entry.

bioRxiv · May 26, 2021Biochemistry

Protein structure analysis of the interactions between SARS-CoV-2 spike protein and the human ACE2 receptor: from conformational changes to novel neutralizing antibodies.

I. Mercurio, V. Tragni, F. Busto, A. De Grassi, C. L. Pierri

This study analyzes SARS-CoV-2 spike protein interactions with human ACE2 receptor using in silico methods to identify and design neutralizing antibodies.

bioRxiv · Apr 17, 2020Biochemistry