Author

V. Velazhahan

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Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

D. Kimanius· 1 shared K. Jamali· 1 shared M. E. Wilkinson· 1 shared S. H. Scheres· 1 shared S. Lövestam· 1 shared T. Nakane· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

D. Kimanius

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1 paper

Recent·Most cited

Data-driven regularisation lowers the size barrier of cryo-EM structure determination

D. Kimanius, K. Jamali, M. E. Wilkinson, S. Lövestam, V. Velazhahan, T. Nakane, S. H. Scheres

This paper introduces a deep-learning-based regularisation method for cryo-EM that improves reconstruction quality, enabling structure determination of smaller macromolecules with low signal-to-noise ratios.

bioRxiv · Oct 23, 2023 · PreprintBiophysics