Loss of PKCtheta-GADD45a axis drives triple-negative breast cancer cells into p53-independent senescence
Amandine Nicolle, Ye Zhang, Valérie Choesmel, Xiaobo Wang, Karine Belguise
This study shows that PKCtheta-GADD45a loss drives p53-independent senescence in TNBC cells by increasing p27 levels.
bioRxiv · Oct 10, 2024 · PreprintCancer Biology