Epigenetic splicing regulation of hTERT mediated by hTAPAS
Valentine Patterson, Alicia Gina Limbach, Julia Aylin Dogruyol, Christiane Kraemer, Lars Erichsen
The paper investigates how DNA methylation and the antisense lncRNA hTAPAS regulate hTERT alternative splicing, revealing an epigenetic mechanism linking promoter methylation to splice isoform selection.
bioRxiv · May 12, 2026 · PreprintMolecular Biology