Single cell tri-channel-processing reveals structural variation landscapes and complex rearrangement processes
Ashley D. Sanders, Sascha Meiers, Maryam Ghareghani, David Porubskỳ, Hyobin Jeong, M. Alexandra C.C. van Vliet, Tobias Rausch, Paulina Richter‐Pechańska, Joachim B. Kunz, Silvia Jenni, Benjamin Raeder, Venla Kinanen, Jürgen Zimmermann, Vladimı́r Beneš, Martin Schrappe, , Jan O. Korbel
This paper introduces scTRIP, a method to detect structural variations in single cells, revealing new SV classes and mutational processes in cancer samples.
bioRxiv · Nov 21, 2019 · PreprintGenomics