Author
German Cancer Research CenterORCID 0000-0003-1953-0848Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Aubrey K. Hubbard, Hélène Neyret‐Kahn, Martina Müller‐Nurasyid…·Mitchell J. Machiela
This study identifies 14 susceptibility loci for Ewing sarcoma through a genome-wide association meta-analysis, revealing genetic interactions with somatic EWSR1::FLI1 fusions.
Alistair A. Poll, Yuzhe Shi, Kerstin Katharina Rauwolf…·Frederik W. van Delft
The paper identifies phospho-LCK (pY394) as a biomarker for dasatinib sensitivity in paediatric T-ALL using flow-cytometry, showing strong correlation with drug response.
Marco Raffaele Cosenza, Alice Gaiatto, Büşra Erarslan-Uysal…·Jan O. Korbel
The paper introduces MAGIC, a platform combining imaging and genomics to study de novo chromosome rearrangements, finding that dicentric chromosomes initiate CA events and TP53 deficiency increases CA rates.
Julia Costea, Kerstin Katharina Rauwolf, Pietro Zafferani…·Jan O. Korbel
This study identifies treatment-resistant stem-like T-ALL cells that expand during relapse using single-cell RNA sequencing of pediatric T-ALL patient samples.
Hyobin Jeong, Karen Grimes, Peter‐Martin Bruch…·Jan O. Korbel
This paper introduces scNOVA, a method to analyze somatic structural variants in single-cell multiomics data, revealing their functional impacts on gene regulation and cancer pathways.
Ashley D. Sanders, Sascha Meiers, Maryam Ghareghani…·Jan O. Korbel
This paper introduces scTRIP, a method to detect structural variations in single cells, revealing new SV classes and mutational processes in cancer samples.