Synaptic Alterations Are Preceding the Axonal Loss in Optic Atrophy of Wolfram Syndrome Mouse Model
Venu Gurram, William An, Shrinivas Bimal, Fumihiko Urano
The paper investigates synaptic and dendritic abnormalities in the retina of Wfs1 knockout mice, finding that synaptic alterations precede axonal loss in a Wolfram syndrome model.
Frontiers in Neuroscience · May 22, 2026Peer-reviewedNeuroscience