Mapping Structural Aging of Human Tissue reveals tissue-specific trajectories and coordinated deterioration
Anamika Yadav, Kyle Alvarez, Kevin Yuk-Lap Yip, Eytan Ruppin, Jacqueline C Yano Maher, Veronica Lobo-Gomez, Caroline Kumsta, Sanju Sinha
The paper introduces PathStAR, a framework to quantify structural aging from histopathology images, revealing tissue-specific aging trajectories and coordinated deterioration across organs.
bioRxiv · Sep 29, 2025 · PreprintBioinformatics