LRP2 is a potential molecular target for pathological myopia
Kimberley Delaunay, Émilie Picard, Patricia Lassiaz, Laurent Jonet, Vidjea Cannaya, José Maria Ruiz Moreno, Kentaro Kojima, Henrik Vorum, Bent Honoré, Jorge Ruiz‐Medrano, Lasse Jørgensen Cehofski, Eric Pussard, Renata Kozyraki, Alicia Torriglia, Olivier Cases, Francine Béhar‐Cohen
This study shows LRP2 levels are reduced in non-syndromic high myopia and posterior staphyloma, and its expression is modulated by light and cortisol.
bioRxiv · Mar 4, 2025 · PreprintPathology