Lysyl oxidase-dependent bone marrow stiffening promotes neutrophil activation in diabetes
Mahesh Agarwal, Sathishkumar Chandrakumar, Vihar Trada, Samanvaya Srivastava, Kaustabh Ghosh
This study shows that diabetes-induced bone marrow stiffening via lysyl oxidase promotes neutrophil activation, which can be inhibited by LOX inhibitors.
bioRxiv · Aug 30, 2025 · PreprintPathology